Contraceptive pills used by women for birth-control could help them lead a longer life with lesser risk of major life-threatening conditions like heart disease and cancer, says a new study.
The study conducted in more than 46,000 women over a period of 40 years showed that contraceptive pills users were less likely to die of heart disease, cancer or a range of other medical ailments.
Prospective cohort study started in 1968 with mortality data supplied by participating general practitioners, National Health Service central registries, or both.
The study published in the British Medical Journal was organized through 1400 general practices throughout the United Kingdom.
A total of 46 112 women were observed for up to 39 years, resulting in 378 006 woman years of observation among never users of oral contraception and 819 175 among ever users.
The study found that 1747 deaths occurred in never users of oral contraception and 2864 in ever users.
Compared with never users, ever users of oral contraception had a significantly lower rate of death from any cause (adjusted relative risk 0.88, 95% confidence interval 0.82 to 0.93).
The users of contraceptives also had significantly lower rates of death from all cancers; large bowel/rectum, uterine body, and ovarian cancer; main gynaecological cancers combined; all circulatory disease; ischaemic heart disease; and all other diseases.
The never users of contraceptive had higher rates of violent deaths. No association between overall mortality and duration of oral contraceptive use was observed, although some disease specific relations were apparent.
An increased relative risk of death from any cause between ever users and never users was observed in women aged under 45 years who had stopped using oral contraceptives 5-9 years previously but not in those with more distant use.
The estimated absolute reduction in all cause mortality among ever users of oral contraception was 52 per 100 000 woman years.
The study concluded that oral contraception was not associated with an increased long term risk of death in this large UK cohort. But a net benefit was apparent.
The balance of risks and benefits, however, may vary globally, depending on patterns of oral contraception usage and background risk of disease.
The research was funded by contraceptive making companies Bayer AG, Pfizer Inc. and Johnson & Johnson besides the Royal College of General Practitioners, Medical Research Council, Imperial Cancer Research Fund, British Heart Foundation, Cruden Foundation.
Oral contraceptive pills are also called birth-control pill or “pill” are used to control pregnancy.
Oral contraceptive pills pills normally contain e, is a birth control method that includes a combination of synthetic sex hormones oestrogen and progestogen.
Oral contraceptive pills pills can stop women from getting pregnant, if taken orally every day.
Oral contraceptive pills were first approved for contraceptive use in the United States in 1960.
Oral contraceptive pills are currently used by more than 100 million women worldwide and by almost 12 million women in the United States.
Some of the common brand names of oral contraceptive pills include Alesse, Apri, Aviane, Brevicon, Demulen, Desogen, Estrostep, Estrostep Fe, Genora, Jenest, Levlen, Levlite, Levora, Lo/Ovral, Loestrin, Loestrin Fe, Low-Ogestrel, Lybrel, Microgestin, Microgestin Fe, Mircette, Modicon, Necon, Norinyl, Nordette, Nortrel, Ogestrel, Ortho-Cept, Ortho-Cyclen, Ortho-Novum, Ortho Tri-Cyclen, Ovcon, Ovral, Seasonale, Seasonique, Tri-Levlen, Tri-Norinyl, Triphasil,
Trivora, Yasmin, Yaz, Zovia etc.