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STEM CELL RESEARCH

Study findings give stem cell research a boost

BY OUR PHARMA CORRESPONDENT


 

June 22, 2007:

Nearly 50% of the patients being treated at fertility clinics in the United States have said that they would be somewhat or very likely to donate their unused embryos for stem cell research.

The findings of a new survey have been published in the journal Science.

The new study was based on a survey of over 1,000 patients at nine fertility centres in the United States which had created and frozen embryos as part of fertility treatment.

Other options, such as having the embryos destroyed or donating them to another infertile couple, appeared less attractive to those surveyed.

The results are in agreement with the sentiments of the majority of the American public, the researchers said.

Now, in case the US legislators permit wider use of unused embryos for stem cell research, 10 times as many embryos would be available for research than previously estimated. President George W Bush has already vetoed a controversial Bill that would have eased federal restrictions on funding for embryonic stem cell research.

Dr Anne Drapkin Lyerly, co-researcher of the study, described the findings of the study as “surprising and dramatic.” She is an associate professor of obstetrics and gynecology at Duke University and core faculty at Duke’s Trent Center for Bioethics, Humanities and History of Medicine.

When asked what they thought they would do with embryos, about 50% of infertility patients said they would be likely to donate some or all of them for stem cell research.

The other author of the study was Ruth Faden, professor of biomedical ethics and director of the Johns Hopkins Berman Institute of Bioethics.

If 25% of the 400,000 frozen embryos believed to be stored in the United States are donated, scientists would get 100,000 embryos (as against 11,000 previously estimated), resulting in 2,000 to 3,000 viable stem cell lines.

Besides, the authors say, the paper adds an important dimension to the debates and controversies surrounding stem cell research.

Embryonic stem cells are pluripotent – which means that they have the ability to develop into virtually any cell type in the body. Researchers hope that these cells may one day yield treatments or cures for diseases such as diabetes, liver failure, spinal injury, stroke, Alzheimer’s disease and heart disease.

However, harvesting stem cells involves destroying a viable embryo, something which many oppose on moral grounds.

Research into embryonic stem cell in the United States has been severely restricted since August 2001, when President George W Bush placed limits on federal funding of the field. Now, federal funds can only be used to study stem cell lines derived from embryos that had been destroyed before that date.

BY OUR PHARMA CORRESPONDENT

 

 
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